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Among other findings, they were able to confirm that: (i) overnight TNF- perfusion increased permeability in HUVECs with upregulation of VCAM-1, ICAM-1, and E-selectin

Since the skin is a living organ, it is susceptible to undergoing changes overtime

The mechanisms in Rickettsia for GSH uptake, GSH breakdown to cysteine, and the connection of GSH to cell division remain unclear and warrant future investigations